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The Vysis ROS1 Break Apart FISH Probe Kit uses Fluorescence in situ hybridization (FISH) technology to detect ROS1 gene rearrangements at 6q22 involving the receptor tyrosine kinase (ROS1) gene. The Vysis ROS 1 Break Apart FISH Probe Kit consists of two fluorophore-labeled DNA probes in TE buffer containing blocking DNA: Vysis 6q22 ROS1 (Cen) SpectrumGreen probe [3′]; Vysis 6q22 ROS1(Tel) SpectrumOrange probe [5′]. The Vysis ROS1 Break Apart FISH Probe Kit consists of two separate probes, located 3' and 5' of the common breakpoint region of the ROS1 gene.
Cancer:
Colorectal Cancer, Gastric Adenocarcinoma, Melanoma, Non Small Cell Lung Cancer
Gene:
ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS)
Method:
Fluorescence in situ hybridization (FISH)